[Neurofibromas in the urogenital system: Report of two cases and literature review.] / Neurofibromas en el sistema urogenital: presentación de dos casos clínicos y revisión de la bibliografía.

OBJECTIVE: We introduce two cases of a 46 and 66-year-old patient, both diagnosed with pelvic neurofibroma (One located in a seminal vesicle, the other in the bladder). The first patient had been diagnosed with Neurofibromatosis type 1 while the other was diagnosed with a sporadic neurofibroma. METHODS: During a study for lower urinary tract symptoms referred, these patients were diagnosed seminal vesicle and bladder neurofibroma, respectively, using image and histological tests. RESULTS: The histopathological and inmunohistochemical characteristics of these benign tumors gave the definitive diagnosis. CONCLUSIONS: Pelvic neurofibromas are a rare entity in this anatomical location. They can be associated with Neurofibromatosis type 1 or not. We get to their diagnosis by an anatomopathological study. Conservative management is the usual procedure, being mandatory a clinical follow-up that must be coupled with image tests.

Neurofibromas en el sistema urogenital: presentación de dos casos clínicos y revisión de la bibliografía / Neurofibromas in the urogenital system: Report of two cases and literature review

OBJETIVO: Se realizó una revisión bilbiográfica en base a dos casos de pacientes de 46 y 66 años diagnosticados de neurofibromas pélvicos (en vesícula seminal y vejiga), siendo uno de ellos esporádico y otro asociado a Neurofibromatosis tipo 1. MÉTODOS: En el contexto del estudio de los pacientes por síntomas del tracto urinario inferior mediante pruebas de imagen y con el estudio anatomopatológico se llegó al diagnóstico de neurofibroma de vesícula seminal y vejiga respectivamente. RESULTADOS: Las características histopatológicas así como las pruebas inmunohistoquímicas permitieron llegar al diagnóstico de este tumor de comportamiento benigno. CONCLUSIONES: Los neurofibromas pélvicos son una entidad rara en esta localización y que pueden aparecer asociados o no a Neurofibromatosis tipo 1. Su diagnóstico se basa en el estudio anatomopatológico y su tratamiento es conservador, precisando un seguimiento clínico y mediante pruebas de imagen

OBJECTIVE: We introduce two cases of a 46 and 66-year-old patient, both diagnosed with pelvic neurofibroma (One located in a seminal vesicle, the other in the bladder). The first patient had been diagnosed with Neurofibromatosis type 1 while the other was diagnosed with a sporadic neurofibroma. METHODS: During a study for lower urinary tract symptoms referred, these patients were diagnosed seminal vesicle and bladder neurofibroma, respectively, using image and histological tests. RESULTS: The histopathological and inmunohistochemical characteristics of these benign tumors gave the definitive diagnosis. CONCLUSIONS: Pelvic neurofibromas are a rare entity in this anatomical location. They can be associated with Neurofibromatosis type 1 or not. We get to their diagnosis by an anatomopathological study. Conservative management is the usual procedure, being mandatory a clinical follow-up that must be coupled with image tests